Program
This Symposium has Concluded
August: 19 | 20 | 21 | 22 | 23 | 24
Saturday, August 19
Symposium and Mini-Symposium Registration
Mendocino I Room, Second Floor Foyer, Hotel Nikko, 222 Mason Street, San Francisco
| 3:00pm | Registration | |
Sunday, August 20
Symposium and Mini-Symposium Registration
Nikko Ballroom Foyer
| 7:30am | Registration | |
Mini-Symposium on Chemical Proteomics
Nikko Ballroom
Chair: Bernhard Küster, Technical University Munich,Freising, Germany
| 8:30am | MS.1 |
Thermal proteome profiling for unbiased assessment of protein state and function in live cells.
Mikhail Savitski, European Molecular Biology Laboratory (EMBL) |
| 9:30 | MS.2 |
SILAC in vitro quantitative profiling of colon cancer spheroids treated with combination chemotherapies in a 3D printed fluidic device.
Amanda Hummon, University of Notre Dame |
| 10:10 | Coffee break | |
| 10:50 | MS.3 |
The target landscape of clinical kinase inhibitors.
Susan Klaeger, The Broad Institute of MIT and Harvard |
| 11:30 | MS.4 |
Towards a comprehensive strategy for target identification of small molecule drug candidates using quantitative chemical proteomics and orthogonal approaches.
Markus Schirle, Novartis Institutes for BioMedical Research |
| 12:10pm | Lunch | |
Chair: Nicholas Hertz, Stanford University, Stanford, CA, USA
| 1:40pm | MS.5 |
Systems Biology of Oncogenic Signaling.
Pedro R. Cutillas, Barts Cancer Institute, Queen Mary University of London |
| 2:20 | MS.6 |
Target ID: successes and lessons learned.
Monica Schenone, The Broad Institute of MIT and Harvard |
| 3:00 | MS.7 |
Chemical-proteomic strategies to investigate reactive cysteines.
Eranthie Weerapana, Boston College |
| 3:40 | MS.8 |
Broad-spectrum kinase profiling in live cells with lysine-targeted chemoproteomic probes.
Jack Taunton, University of California, San Francisco |
Nikko Ballroom Vestibule
| 4:00pm | Symposium Registration | |
Monterey & Carmel Rooms
| 4:00pm | Symposium Poster Set-up | |
Golden Gate Room, 25th floor
| 6:00pm | Opening Reception | |
Monday, August 21
Nikko Ballroom Foyer
| 7:30am | Registration | |
Symposium: Emerging Challenges in Medicine and Biology
Nikko Ballroom
| 8:15am |
Introduction
A.L. Burlingame, Steven A. Carr and Bernhard Küster |
|
Chair: Steven A. Carr, The Broad Institute of MIT and Harvard, Cambridge, MA, USA
| 8:30am | 1.1 |
Plenary Lecture Identifying and Targeting Tumor Neoantigens. Catherine Wu, Harvard Medical School |
Chair: Robert Chalkley, University of California, San Francisco, CA, USA
| 9:30am | 1.2 |
Mapping the Glycoproteome with Activated Ion Electron Transfer Dissociation.
Joshua Coon, University of Wisconsin-Madison |
| 10:10 | Coffee break | |
| 10:30 | 1.3 |
Highly multiplexed and targeted imaging of tissues my mass cytometry.
Bernd Bodenmiller, Institute of Molecular Life Science, University of Zurich |
| 11:10 | 1.4 |
Pulsed SILAC and TMT labeling reveals proteoform resolved protein dynamics.
Bernhard Küster, Technical University Munich |
| 11:50 | 1.5 |
Evolution, dynamics and genetics of protein post-translational control.
Pedro Beltrao, European Bioinformatics Institute (EMBL-EBI) |
| 12:30pm | Lunch | |
Chair: Joshua Coon, University of Wisconsin-Madison, Madison, WI, USA
| 2:00pm | 2.1 |
Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS.
Tony Ly, University of Dundee |
| 2:40 | 2.2 |
Proteome dynamics.
Matthias Selbach, Max-Delbrück-Center for Molecular Medicine(MDC) |
| 3:20 | 2.3 |
Quantitative profiling of highly polymorphic multigene products.
Rob Beynon, Institute of Integrative Biology, University of Liverpool |
Symposium Poster Session A
Monterey & Carmel Rooms
Co-Chairs: Juan Oses-Prieto and Jason Maynard, University of California, San Francisco, CA, USA
| 4:00pm | Poster Session A | |
Tuesday, August 22
Symposium: Methodologies Enabling New Insights into Biology I
Nikko Ballroom
Chair: Steven A. Carr, The Broad Institute of MIT and Harvard, Cambridge, MA, USA
| 8:30am | 3.1 |
FLASH TALKS |
Chair: Donald Kirkpatrick, Genentech, South San Francisco, CA, USA
| 9:30am | 3.2 |
Quantifying Ubiquitin Signaling for Mitophagy.
Wade Harper, Harvard Medical School |
| 10:10 | Coffee break | |
| 10:30 | 3.3 |
Spatial proteomics and transcriptomics.
Alice Y. Ting, Stanford University |
| 11:10 | 3.4 |
High-density proximity interactome mapping at
steady-state reveals the subcellular organization of mRNA
associated granules and bodies
Anne-Claude Gingras, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital |
| 11:50 | 3.5 |
MCP Lecturer Hybrid mass spectrometry approaches targeting cellular signaling. Albert J. R. Heck, Utrecht University |
| 12:30pm | Lunch | |
| 12:30pm | Thermo Fisher Lunch | |
Chair: Albert J.R. Heck, Utrecht University, Utrecht, The Netherlands
| 2:00pm | 4.1 |
Role of mediator in transcription control.
Philip Robinson, Stanford University Medical School |
| 2:40 | 4.2 |
Chemical crosslinking based integrative structural biology of the Mediator complex and higher order transcription complexes.
Michael Trnka, University of California, San Francisco |
| 3:20 | 4.3 |
N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis.
Michiel Vermeulen, Radboud University |
Symposium Poster Session B
Monterey & Carmel Rooms
Co-Chairs: Robert Chalkley and Giselle Knudsen, University of California, San Francisco, CA, USA
| 4:00pm | Poster Session B | |
Wednesday, August 23
Symposium: Methodologies Enabling New Insights into Biology II
Nikko Ballroom
Chair: Samuel Myers, The Broad Institute of MIT and Harvard, Cambridge, MA, USA
| 8:30am | 5.1 |
Using Nanoflow LC-MS/MS to Study Metabolic Changes in Low Grade Astrocytoma.
Thomas A. Neubert, New York University School of Medicine |
| 9:10 | 5.2 |
Degradomics analysis reveals a neuron specific death domain containing protein that is a caspase 3 cleavage target required for axon degeneration.
Nicholas Hertz, Stanford University |
| 9:50 | 5.3 |
Updates from the NO-Seq Zone: Translatome Proteomics in Nerve Axons.
Michael Fainzilber, The Weizmann Institute of Science |
| 10:30 | Coffee break | |
Chair: Anne-Claude Gingras, Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Toronto, ON, Canada
| 10:50am | 5.4 |
Plenary Lecture Proteomics technologies for signaling and clinical applications Matthias Mann, Max Planck Institute of Biochemistry and Novo Nordisk Foundation Center for Protein Research |
| 11:50 | Lunch | |
Chair: Nicholas Hertz, Stanford University, Stanford, CA, USA
| 1:20pm | 6.1 |
Revealing nascent proteomics in vivo in signaling pathways and cell differentiation.
Craig Forester, University of California, San Francisco |
| 2:00 | 6.2 |
CRISPR/Cas9-APEX-mediated proximity labeling enables discovery of proteins associated with a predefined genomic locus.
Samuel Myers, The Broad Institute of MIT and Harvard |
| 2:40 | 6.3 |
Growth Factors, Cell Signaling and the rise of
Proteomics
Ralph Bradshaw, University of California, San Diego |
Conference Dinner
General’s Residence, Fort Mason
| 6:00pm |
Conference Dinner Reception
General’s Residence, Fort Mason, Presidio, San Francisco |
|
| 7:00 |
Conference Dinner
General’s Residence, Fort Mason, Presidio, San Francisco |
|
Thursday, August 24
Symposium: Methodologies Enabling New Insights into Biology III
Nikko Ballroom
Chair: Robert Beynon, Institute of Integrative Biology, University of Liverpool, England, United Kingdom
| 8:30am | 7.1 |
On the hunt for cancer neoantigens: is mass spectrometry the solution?
Josh Elias, Stanford University |
| 9:10 | 7.2 |
Improvement of sensitivity and comprehensiveness of proteomic analyses using a novel FAIMS interface.
Pierre Thibault, Universite de Montreal |
| 9:50 | 7.3 |
Dynamic proteome organization and host defense during viral infection.
Ileana M. Cristea, Princeton University |
| 10:30 | Coffee break | |
| 11:00 | 7.4 |
Structural Analysis of the 26S Proteasome Complex to Understand its Function and Regulation.
Lan Huang, University of California, Irvine |
| 11:40 | Lunch | |
Chair: Anatoly Urisman, University of California, San Francisco, CA, USA
| 1:40pm | 8.1 |
Towards a new diagnostic tool for urinary tract infection using LC-MSMS in Data Independent Acquisition mode and bacterial specific spectral libraries.
Florence Roux-Dalvai, Centre de Recherche du CHU de Québec, Centre Hospitalier de l'Université Laval |
| 2:20 | 8.2 |
Clinical proteomics of response to anti-cancer treatment reveals metabolic control of treatment resistance.
Tamar Geiger, Sackler Faculty of Medicine, Tel Aviv University |
| 3:00 | 8.3 |
Opposing effects of cancer type-specific SPOP mutations on BET protein degradation and sensitivity to BET inhibitors.
Namarata Udeshi, The Broad Institute of MIT and Harvard |
Chair: Steven A. Carr, The Broad Institute of MIT and Harvard, Cambridge, MA, USA
| 3:40pm | 8.4 |
Plenary Lecture Targeted protein degradation induced by thalidomide analogs Benjamin Ebert, Harvard Medical School |
| 4:40pm | Closing remarks | |
| 5:00 | Adjourn | |
