Posters

This Symposium has Concluded

The Poster Listing from the Twelfth Symposium

Poster Session A

A.1	PPKs mediate direct signal transfer from phytochrome photoreceptors to transcription factor PIF3. W Ni*, S-L Xu, E González-Grandio, RJ Chalkley, AFR Humer, AL Burlingame, Z-Y Wang, PH Quail
A.2	Mass Spectrometry-based Proteomics of Human Breast Milk to Identify Potential Breast Cancer Biomarkers. R Aslebagh*, D Channaveerappa, KF Arcaro, CC Darie
A.3	Profiling Biochemical Individuality: Human Personal Omics Profiling (hPOP). S Ahadi*, H Rost, L Liang, M Snyder
A.4	Towards a Human Chemo-proteomic Database: Profiling Structurally Diverse Chemical Space to Map Proteome-wide Interactions. F Garcia*, K Cheon, H Wang, A Liaw, V Mishra, AM Wassermann, B Dill, B Ruprecht, A Chi, X Qiao, I Cornella-Taracido
A.5	Development of Quantitative Mass Spectrometry Assays for Species-matched Surrogate Antibody Fragments in Ocular Matrices. H Hernandez-Barry*, RF Kelley, D Tesar, W Shatz, L Comps-Agrar, J Chan, K Xu, L Liu, Y Liu, M Maia, K Loyet
A.6	The functional landscape of human protein phosphorylation. D Ochoa*, A Jarnuczak, JA Jizaíno, P Beltrao
A.7	Direct Proximity Tagging of Small Molecule Protein Targets. Z Hill*, SB Pollock, M Zhuang, JA Wells
A.8	iST: a reproducible sample preparation method for in-depth proteome discovery and interaction proteomics. D Pichler*, F Hosp, N Kulak, M Mann
A.9	Requirements of O-GlcNAcylation in hepatocytes and liver metabolic function. K Kaasik*, R Chalkley, AL Burlingame
A.10	A Tale of Two – Data Independent Acquisition applied to maximize proteome coverage and throughput. RM Bruderer, OM Bernhardt, T Gandhi, J Muntel, S Müller, P Mironova, O Walter, J Carayol, J Hager, A Valsesia, L Dayon, A Astrup, WHM Saris, F Marty*, L Reiter
A.11	Quantifying early events on mitochondria in the PINK1/PARKIN ubiquitin ligase signaling cascade. A Ordureau*, JA Paulo, J Zhang, W Harper
A.12	Pyrraline, Argpyrimidine and carboxymethyllysine adducts of advanced glycated apoA-IV do not change the apolipoprotein ability in removing cell cholesterol and inhibiting inflammation in macrophages. LS Okuda*, R Pickford, M Patel, T Woods, M Brimble, K-A Rye, M Passarelli
A.13	High-Throughput Screening of Proteoform-Specific Binding of a Chemical Library. D Wang*, G Gil, P Mao
A.14	Accurate measurement of acetylation stoichiometry by quantitative MS. B Weinert*, C Choudhary, B Karbech Hansen
A.15	Extraction and Characterization of Prenylated Proteins. J Wilkins*, AL Burlingame
A.16	Profiling the Distribution of N-Glycosylation in Therapeutic Antibodies using LC or CE separation in combination with a QTRAP® 6500 System. J Albanese*, CL Hunter, NS Meitei, A Guttman, M Szigeti
A.17	Identifying the N-terminal acetyltransferases involved in N-terminal Acetylation of RNA polymerase II subunits. A Saraf*, A Mosley, Y Hao, MP Washburn, L Florens
A.18	Deciphering the Mechanism of Interferon Regulation in pDCs Using Phospho and Ubiquitin Remnant Motif Proteomics. DM Walther*, A Pellerin, K Li, D Rabah, P Juhasz
A.19	Ancient regulatory role of lysine acetylation. S Payne*, ES Nakayasu
A.20	Mechanistic characterization of key factors that drive antibody drug conjugate in vitro efficacy: intracellular payload deconjugation and accumulation relative to free drug potency. J dela Cruz-Chuh*, Y Liu, KR Kozak
A.21	Label-free Quantification of Nascent Proteins in Primary Astrocyte Cells by Incorporation of O-Propargyl-puromycin, Affinity Purification, and LC-MS/MS Analysis. I Koppel, NJ Phillips*, Q Zhao, RJ Chalkley, JA Oses-Prieto, M Fainzilber, A. Burlingame
A.22	Multiple QconCAT biosynthesis in a cell-free protein synthesis system. N Takemori*, A Takemori, Y Tanaka, Y Endo, JL Hurst, G Gómez-Baena, VM Harman, RJ Beynon
A.23	Defining the Cell Surface Proteome of MLL Rearranged Leukemia. M Nix*, AP Wiita
A.24	Reliable protein quantification in the OpenMS software framework. L Nilse*, O Schilling, M Biniossek
A.25	Engineering peptide ligase specificity to enable unbiased global sequencing of proteolytic cleavage sites. A Weeks*, JA Wells
A.26	Mitochondrial ATP synthase disorders investigated by quantitative proteomics of CRISPR-Cas9 knockout cell lines. M Vrbacky*, J Kovalcikova, K Harant, A Pecinova, J Houstek, T Mracek
A.27	Modification site-specific pathway analysis applied to phosphoproteomes detects unique perturbation signatures that are not accessible to gene-centric pathway analysis. K Krug*, P Mertins, B Zhang, P Hornbeck, R Raju, R Ahmad, M Szucs, P Tamayo, JP Mesirov, JD Jaffe, SA Carr, DR Mani
A.28	Identification of Novel Autoantigens in Autoimmune Encephalitis. G Knudsen*, C Mandel-Brehm, C Liverman, Y Schollmeier, BD O'Donovan, T Huynh, SJ Pleasure, MR Wilson, AL Burlingame, JL DeRisi
A.29	Combined Top-down and Bottom-up Proteomics using Capillary Electrophoresis–Mass Spectrometry. C-H Chen*, A Gajadhar, I Ntai, A Huhmer
A.30	AltitudeOmics: Red Blood Cell Metabolic Adaptation to High Altitude Hypoxia. T Nemkov*, A D'Alessandro, AA Monte, AW Subhudi, AT Lovering, KC Hansen, RC Roach
A.31	Sharing Annotated Spectra when Standard Formats are not an Option. RJ Chalkley*, P Baker
A.32	Characterizing covalent protein-DNA adducts in the human cell. E Myers*, K Kiianitsa, N Maizels, S-E Ong
A.33	Unbiased phosphoproteomics reveals a therapeutically-relevant connection between pre-mRNA splicing and proteasome inhibition in multiple myeloma. HH Huang*, C Lam, A Thornton, M Mariano, I Ferguson, BC Hann, AN Brooks, AP Wiita
A.34	Unraveling White Lupin's Signal Transduction in Response to Phosphorus Deficiency using iTRAQ Labeling, Phosphopeptide Enrichment, and Tandem Mass Spectrometry. M Amadi*, C Uhde-Stone, K Li, R Chalkley, AL Burlingame
A.35	Identification of Lysyl Oxidase Generated Protein Crosslinks in Collagen. K Hansen*, A Barrett, P Baker, R Chalkley
A.36	Top-down strategies to better localize post-translational modifications of integral membrane proteins. J Whitelegge*

Poster Session B

B.1	Nutrient Regulation of Transcription & Signaling by O-GlcNAc: Fundamental Roles in Diabetes, Neurodegeneration and Cancer. G Hart*
B.2	Characterization of Glycoproteins by Top Down UVPD Analysis. C Going*, R Huguet, D Lopez Ferrer, V Zabrouskov, AF Huhmer, S Pitteri
B.3	Proteomics as a Tool for Biological Forensics. E Merkley*, SC Jenson, DS Wunschel, KL Wahl, N Heller, KH Jarman
B.4	Spectral Library of Mouse Brain Proteome. S Guan*, N Johnson, J Chen, AL Burlingame
B.5	Specter: linear deconvolution as a new paradigm for targeted analysis of data-independent acquisition mass spectrometry proteomics. R Peckner*, SA Myers, JD Egertson, RS Johnson, SA Carr, MJ MacCoss, JD Jaffe
B.6	Targeting RAS Driven Cancers with Antibodies to Upregulated and Functionally Important Cell-Surface Proteins. AJ Martinko*, C Truillet, O Julien, J Diaz, M Horlbeck, G Whiteley, J Blonder, J Weissman, S Bandyopadhyay, M Evans, JA Wells
B.7	Defining Kinase Inhibitor Polypharmacology with Multiplexed Inhibitor Bead Proteomics: Abemaciclib Inhibits Glycogen Synthase Kinase 3 Beta to Activate WNT Signaling. EM Cousins*, D Goldfarb, F Yan, J Roques, D Darr, GL Johnson, MB Major
B.8	Large-scale phosphoproteomics reveals Shp2 phosphatase-dependent regulators of Pdgf receptor signaling. TS Batth*, M Papetti, A Pfeiffer, C Francavilla, JV Olsen
B.9	Identification of Predictive Biomarkers For Radiation Injury From Circulating Serum And Urine Exosomes. E Chen*, A Ribault, S Kulkarni, A Koller
B.10	Quantitative comparison of the O-GlcNAcome in Female and Male Embryonic Stem Cells. JC Maynard*, EA Martin, B Panning, AL Burlingame
B.11	Investigation of novel MELK interacting proteins and signaling pathways in triple-negative breast cancer. IM McDonald*, RC Martinez Chacin, X Wang, LE Herring, MJ Emanuele, LM Graves
B.12	Characterizing the inducible degradation of mutant PIK3CA using mass spectrometry. L Phu*, KA Edgar, K Song, W Forrest, L Friedman, DS Kirkpatrick
B.13	High throughput proteomics approach reveals mechanistic basis of acute viral pathogenesis mediated by an RNAi suppressor protein in insect cells. A Nayak*, M Trnka, K Li, C Kerr, E Jan, AL Burlingame, R Andino
B.14	Chemoproteomic Approaches Toward Small Molecule Support in Drug Discovery. V Pham*, J Crawford, K Edgar, L Friedman, N Ghilardi, A Johnson, A Katewa, W Lee, S Staben, W Young, JR Lill
B.15	Proximity biotinylation identifies protein factors associated with the mitochondrial genome in living cells. S Han*, N Udeshi, T Deerinck, T Svinkina, M Ellisman, S Carr, A Ting
B.16	Protein interaction network of ERα and AP-2γ in breast cancer cells. E Cheung*, G Cui, B Poudel, M Lam, K Lei, T Poon
B.17	An optimized protocol for global proteome and phosphoproteome analysis that yields highly reproducible and deep coverage within and across laboratories. LC Tang*, P Mertins, MA Gillette, T Liu, H Zhang, MA Gritsenko, TR Clauss, P Shah, L Chen, KR Clauser, F Mundt, SA Carr
B.18	The Power of Quantitative Multiplexing - Combining TMT discovery and targeted label free workflows for biomarker analysis. A Gajadhar*, X Jiang, S Snovida, D Horn, V Spicer, O Krokhin, R Viner, A Huhmer
B.19	Global proteomic and transcriptomic analysis of the LRRK2 G2019S mutation in iPSC-derived midbrain dopaminergic neurons. J Martin*, H Booth, B Gao, K Li, C Roberts, N Allaire, J Vowles, S Cowley, P Juhasz, R Wade-Martins, WD Hirst
B.20	Uncovering protein networks in microbial systems: a possible functional link between protein translation and the biosynthesis of Fe-S cluster in Azotobacter vinelandii. C Zheng*, B Buchanan, PC Dos Santos
B.21	The Missing Link: methods for analysis of proteins bound to long non-coding RNAs. C Hartigan*, M Munschauer, M Schenone, SA Carr, ES Lander
B.22	Proteomics workflow using dissolvable polyacrylamide gels. A Takemori*, N Takemori, P Wongkongkathep, M Nshanian,RR Ogorzalek Loo, F Lermyte, S Wu, JA Loo
B.23	Multi-omics study of medulloblastoma. T Archer, T Ehrenberger, F Mundt*, K Krug, P Mertins, DR Mani, M Gillette, K Clauser, M Gold, P Tamayo, P Northcott, S Pfister, SL Pomeroy, JP Mesirov, S Carr, E Fraenkel
B.24	Phospho-proteomics study of AMPK signaling pathway. Zhen Chen*, Caoqi Lei, Junjie Chen
B.25	Multi-omics of Acute Myeloid Leukemia Hypomethylation by Azacitidine. K Leung*, A Nguyen, T Shi, L Tang, L Escoubet, K MacBeth, J DiMartino, J Wells
B.26	In-cell chemical crosslinking identifies hotspots for p62-IκBα interaction and reveals the critical role of p62 in IκBα-mediated NFκB transcriptional repression. Y Liu*, M Trnka, D Kwon, JP Grenert, MA Correia
B.27	Clinical applications of universal S-Trap sample processing. J Wilson*, NS Turna, R Banks, DJC Pappin, A Zougman
B.28	Approximating isotopic distributions of biomolecule fragment ions. D Goldfarb*, M Lafferty, L Herring, W Wang, MB Major
B.29	Developing a quantitative mass spectrometric-based assay to monitor global deubiquitinase activities in response to DUB inhibitor perturbation. T Ma*, D Hewings, B Forrest, J Heideker, L Kategaya, A Fedorova, O Huang, J Lill, IE Wertz, K Yu
B.30	Antibodies to biotin enable large-scale detection of biotinylation sites on proteins. T Svinkina*, ND Udeshi, K Pedram, S Fereshetian, SA Myers, O Aygun, K Krug, K Clauser, D Ryan, T Ast, VK Mootha, AY Ting, SA Carr
B.31	Direct in-gel profiling of protease specificity - DIPPS. R Vidmar*, M Vizovisek, D Turk, B Turk, M Fonovic
B.32	Identification of the Hedgehog Signalling Modulator Dynarrestin. S Höing, T-Y Yeh, M Baumann, N Martinez, L Kremer, HCA Drexler*, P Kuchler, S Ziegler, P Reinhardt, P Habenberger, A Choidas, M Zischinsky, G Zischinsky, L Wagner, RM Abo-Rady, P Nussbaumer, B Klebl, T Schroer, HR Schöler, H Maldmann, JL Sterneckert
B.33	Comprehensive proteome characterization and improved strategies for multi-PTM analysis. J Oses-Prieto*, J Maynard, S Chand, AL Burlingame
B.34	Library-Free DIA for PTM Identification and Quantification using PIQED: Application to Multiple Diet-Induced Acylation Changes in Mouse Liver Mitochondrial Proteins. JG Meyer*, S Softic, N Basisty, G-X Wang, S Mukkamalla, H Steen, AI Nesvizhskii, E Verdin, BW Gibson, CB Newgard, CR Kahn, B Schilling
B.35	Quantitative proteomic characterization of an isogenic model of the 22q11.2 syndrome deletion generated by CRISPR/Cas9 engineering. Y-H Lin*, NP Paranjape, AP Wiita
B.36	Coupling Semi-preparative SEC MS: Analysis of reduced and alkylated mAbs. JH Robinson*, JO Hui, IDG Campuzano

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