| A.1 |
PPKs mediate direct signal transfer from phytochrome photoreceptors to transcription factor PIF3.
W Ni*, S-L Xu, E González-Grandio, RJ Chalkley, AFR Humer, AL Burlingame, Z-Y Wang, PH Quail
|
| A.2 |
Mass Spectrometry-based Proteomics of Human Breast Milk to Identify Potential Breast Cancer Biomarkers.
R Aslebagh*, D Channaveerappa, KF Arcaro, CC Darie
|
| A.3 |
Profiling Biochemical Individuality: Human Personal Omics Profiling (hPOP).
S Ahadi*, H Rost, L Liang, M Snyder
|
| A.4 |
Towards a Human Chemo-proteomic Database: Profiling Structurally Diverse Chemical Space to Map Proteome-wide Interactions.
F Garcia*, K Cheon, H Wang, A Liaw, V Mishra, AM Wassermann, B Dill, B Ruprecht, A Chi, X Qiao, I Cornella-Taracido
|
| A.5 |
Development of Quantitative Mass Spectrometry Assays for Species-matched Surrogate Antibody Fragments in Ocular Matrices.
H Hernandez-Barry*, RF Kelley, D Tesar, W Shatz, L Comps-Agrar, J Chan, K Xu, L Liu, Y Liu, M Maia, K Loyet
|
| A.6 |
The functional landscape of human protein phosphorylation.
D Ochoa*, A Jarnuczak, JA Jizaíno, P Beltrao
|
| A.7 |
Direct Proximity Tagging of Small Molecule Protein Targets.
Z Hill*, SB Pollock, M Zhuang, JA Wells
|
| A.8 |
iST: a reproducible sample preparation method for in-depth proteome discovery and interaction proteomics.
D Pichler*, F Hosp, N Kulak, M Mann
|
| A.9 |
Requirements of O-GlcNAcylation in hepatocytes and liver metabolic function.
K Kaasik*, R Chalkley, AL Burlingame
|
| A.10 |
A Tale of Two – Data Independent Acquisition applied to maximize proteome coverage and throughput.
RM Bruderer, OM Bernhardt, T Gandhi, J Muntel, S Müller, P Mironova, O Walter, J Carayol, J Hager, A Valsesia, L Dayon, A Astrup, WHM Saris, F Marty*, L Reiter
|
| A.11 |
Quantifying early events on mitochondria in the PINK1/PARKIN ubiquitin ligase signaling cascade.
A Ordureau*, JA Paulo, J Zhang, W Harper
|
| A.12 |
Pyrraline, Argpyrimidine and carboxymethyllysine adducts of advanced glycated apoA-IV do not change the apolipoprotein ability in removing cell cholesterol and inhibiting inflammation in macrophages.
LS Okuda*, R Pickford, M Patel, T Woods, M Brimble, K-A Rye, M Passarelli
|
| A.13 |
High-Throughput Screening of Proteoform-Specific Binding of a Chemical Library.
D Wang*, G Gil, P Mao
|
| A.14 |
Accurate measurement of acetylation stoichiometry by quantitative MS.
B Weinert*, C Choudhary, B Karbech Hansen
|
| A.15 |
Extraction and Characterization of Prenylated Proteins.
J Wilkins*, AL Burlingame
|
| A.16 |
Profiling the Distribution of N-Glycosylation in Therapeutic Antibodies using LC or CE separation in combination with a QTRAP® 6500 System.
J Albanese*, CL Hunter, NS Meitei, A Guttman, M Szigeti
|
| A.17 |
Identifying the N-terminal acetyltransferases involved in N-terminal Acetylation of RNA polymerase II subunits.
A Saraf*, A Mosley, Y Hao, MP Washburn, L Florens
|
| A.18 |
Deciphering the Mechanism of Interferon Regulation in pDCs Using Phospho and Ubiquitin Remnant Motif Proteomics.
DM Walther*, A Pellerin, K Li, D Rabah, P Juhasz
|
| A.19 |
Ancient regulatory role of lysine acetylation.
S Payne*, ES Nakayasu
|
| A.20 |
Mechanistic characterization of key factors that drive antibody drug conjugate in vitro efficacy: intracellular payload deconjugation and accumulation relative to free drug potency.
J dela Cruz-Chuh*, Y Liu, KR Kozak
|
| A.21 |
Label-free Quantification of Nascent Proteins in Primary Astrocyte Cells by Incorporation of O-Propargyl-puromycin, Affinity Purification, and LC-MS/MS Analysis.
I Koppel, NJ Phillips*, Q Zhao, RJ Chalkley, JA Oses-Prieto, M Fainzilber, A. Burlingame
|
| A.22 |
Multiple QconCAT biosynthesis in a cell-free protein synthesis system.
N Takemori*, A Takemori, Y Tanaka, Y Endo, JL Hurst, G Gómez-Baena, VM Harman, RJ Beynon
|
| A.23 |
Defining the Cell Surface Proteome of MLL Rearranged Leukemia.
M Nix*, AP Wiita
|
| A.24 |
Reliable protein quantification in the OpenMS software framework.
L Nilse*, O Schilling, M Biniossek
|
| A.25 |
Engineering peptide ligase specificity to enable unbiased global sequencing of proteolytic cleavage sites.
A Weeks*, JA Wells
|
| A.26 |
Mitochondrial ATP synthase disorders investigated by quantitative proteomics of CRISPR-Cas9 knockout cell lines.
M Vrbacky*, J Kovalcikova, K Harant, A Pecinova, J Houstek, T Mracek
|
| A.27 |
Modification site-specific pathway analysis applied to phosphoproteomes detects unique perturbation signatures that are not accessible to gene-centric pathway analysis.
K Krug*, P Mertins, B Zhang, P Hornbeck, R Raju, R Ahmad, M Szucs, P Tamayo, JP Mesirov, JD Jaffe, SA Carr, DR Mani
|
| A.28 |
Identification of Novel Autoantigens in Autoimmune Encephalitis.
G Knudsen*, C Mandel-Brehm, C Liverman, Y Schollmeier, BD O'Donovan, T Huynh, SJ Pleasure, MR Wilson, AL Burlingame, JL DeRisi
|
| A.29 |
Combined Top-down and Bottom-up Proteomics using Capillary Electrophoresis–Mass Spectrometry.
C-H Chen*, A Gajadhar, I Ntai, A Huhmer
|
| A.30 |
AltitudeOmics: Red Blood Cell Metabolic Adaptation to High Altitude Hypoxia.
T Nemkov*, A D'Alessandro, AA Monte, AW Subhudi, AT Lovering, KC Hansen, RC Roach
|
| A.31 |
Sharing Annotated Spectra when Standard Formats are not an Option.
RJ Chalkley*, P Baker
|
| A.32 |
Characterizing covalent protein-DNA adducts in the human cell.
E Myers*, K Kiianitsa, N Maizels, S-E Ong
|
| A.33 |
Unbiased phosphoproteomics reveals a therapeutically-relevant connection between pre-mRNA splicing and proteasome inhibition in multiple myeloma.
HH Huang*, C Lam, A Thornton, M Mariano, I Ferguson, BC Hann, AN Brooks, AP Wiita
|
| A.34 |
Unraveling White Lupin's Signal Transduction in Response to Phosphorus Deficiency using iTRAQ Labeling, Phosphopeptide Enrichment, and Tandem Mass Spectrometry.
M Amadi*, C Uhde-Stone, K Li, R Chalkley, AL Burlingame
|
| A.35 |
Identification of Lysyl Oxidase Generated Protein Crosslinks in Collagen.
K Hansen*, A Barrett, P Baker, R Chalkley
|
| A.36 |
Top-down strategies to better localize post-translational modifications of integral membrane proteins.
J Whitelegge*
|
| B.1 |
Nutrient Regulation of Transcription & Signaling by O-GlcNAc: Fundamental Roles in Diabetes, Neurodegeneration and Cancer.
G Hart*
|
| B.2 |
Characterization of Glycoproteins by Top Down UVPD Analysis.
C Going*, R Huguet, D Lopez Ferrer, V Zabrouskov, AF Huhmer, S Pitteri
|
| B.3 |
Proteomics as a Tool for Biological Forensics.
E Merkley*, SC Jenson, DS Wunschel, KL Wahl, N Heller, KH Jarman
|
| B.4 |
Spectral Library of Mouse Brain Proteome.
S Guan*, N Johnson, J Chen, AL Burlingame
|
| B.5 |
Specter: linear deconvolution as a new paradigm for targeted analysis of data-independent acquisition mass spectrometry proteomics.
R Peckner*, SA Myers, JD Egertson, RS Johnson, SA Carr, MJ MacCoss, JD Jaffe
|
| B.6 |
Targeting RAS Driven Cancers with Antibodies to Upregulated and Functionally Important Cell-Surface Proteins.
AJ Martinko*, C Truillet, O Julien, J Diaz, M Horlbeck, G Whiteley, J Blonder, J Weissman, S Bandyopadhyay, M Evans, JA Wells
|
| B.7 |
Defining Kinase Inhibitor Polypharmacology with Multiplexed Inhibitor Bead Proteomics: Abemaciclib Inhibits Glycogen Synthase Kinase 3 Beta to Activate WNT Signaling.
EM Cousins*, D Goldfarb, F Yan, J Roques, D Darr, GL Johnson, MB Major
|
| B.8 |
Large-scale phosphoproteomics reveals Shp2 phosphatase-dependent regulators of Pdgf receptor signaling.
TS Batth*, M Papetti, A Pfeiffer, C Francavilla, JV Olsen
|
| B.9 |
Identification of Predictive Biomarkers For Radiation Injury From Circulating Serum And Urine Exosomes.
E Chen*, A Ribault, S Kulkarni, A Koller
|
| B.10 |
Quantitative comparison of the O-GlcNAcome in Female and Male Embryonic Stem Cells.
JC Maynard*, EA Martin, B Panning, AL Burlingame
|
| B.11 |
Investigation of novel MELK interacting proteins and signaling pathways in triple-negative breast cancer.
IM McDonald*, RC Martinez Chacin, X Wang, LE Herring, MJ Emanuele, LM Graves
|
| B.12 |
Characterizing the inducible degradation of mutant PIK3CA using mass spectrometry.
L Phu*, KA Edgar, K Song, W Forrest, L Friedman, DS Kirkpatrick
|
| B.13 |
High throughput proteomics approach reveals mechanistic basis of acute viral pathogenesis mediated by an RNAi suppressor protein in insect cells.
A Nayak*, M Trnka, K Li, C Kerr, E Jan, AL Burlingame, R Andino
|
| B.14 |
Chemoproteomic Approaches Toward Small Molecule Support in Drug Discovery.
V Pham*, J Crawford, K Edgar, L Friedman, N Ghilardi, A Johnson, A Katewa, W Lee, S Staben, W Young, JR Lill
|
| B.15 |
Proximity biotinylation identifies protein factors associated with the mitochondrial genome in living cells.
S Han*, N Udeshi, T Deerinck, T Svinkina, M Ellisman, S Carr, A Ting
|
| B.16 |
Protein interaction network of ERα and AP-2γ in breast cancer cells.
E Cheung*, G Cui, B Poudel, M Lam, K Lei, T Poon
|
| B.17 |
An optimized protocol for global proteome and phosphoproteome analysis that yields highly reproducible and deep coverage within and across laboratories.
LC Tang*, P Mertins, MA Gillette, T Liu, H Zhang, MA Gritsenko, TR Clauss, P Shah, L Chen, KR Clauser, F Mundt, SA Carr
|
| B.18 |
The Power of Quantitative Multiplexing - Combining TMT discovery and targeted label free workflows for biomarker analysis.
A Gajadhar*, X Jiang, S Snovida, D Horn, V Spicer, O Krokhin, R Viner, A Huhmer
|
| B.19 |
Global proteomic and transcriptomic analysis of the LRRK2 G2019S mutation in iPSC-derived midbrain dopaminergic neurons.
J Martin*, H Booth, B Gao, K Li, C Roberts, N Allaire, J Vowles, S Cowley, P Juhasz, R Wade-Martins, WD Hirst
|
| B.20 |
Uncovering protein networks in microbial systems: a possible functional link between protein translation and the biosynthesis of Fe-S cluster in Azotobacter vinelandii.
C Zheng*, B Buchanan, PC Dos Santos
|
| B.21 |
The Missing Link: methods for analysis of proteins bound to long non-coding RNAs.
C Hartigan*, M Munschauer, M Schenone, SA Carr, ES Lander
|
| B.22 |
Proteomics workflow using dissolvable polyacrylamide gels.
A Takemori*, N Takemori, P Wongkongkathep, M Nshanian,RR Ogorzalek Loo, F Lermyte, S Wu, JA Loo
|
| B.23 |
Multi-omics study of medulloblastoma.
T Archer, T Ehrenberger, F Mundt*, K Krug, P Mertins, DR Mani, M Gillette, K Clauser, M Gold, P Tamayo, P Northcott, S Pfister, SL Pomeroy, JP Mesirov, S Carr, E Fraenkel
|
| B.24 |
Phospho-proteomics study of AMPK signaling pathway.
Zhen Chen*, Caoqi Lei, Junjie Chen
|
| B.25 |
Multi-omics of Acute Myeloid Leukemia Hypomethylation by Azacitidine.
K Leung*, A Nguyen, T Shi, L Tang, L Escoubet, K MacBeth, J DiMartino, J Wells
|
| B.26 |
In-cell chemical crosslinking identifies hotspots for p62-IκBα interaction and reveals the critical role of p62 in IκBα-mediated NFκB transcriptional repression.
Y Liu*, M Trnka, D Kwon, JP Grenert, MA Correia
|
| B.27 |
Clinical applications of universal S-Trap sample processing.
J Wilson*, NS Turna, R Banks, DJC Pappin, A Zougman
|
| B.28 |
Approximating isotopic distributions of biomolecule fragment ions.
D Goldfarb*, M Lafferty, L Herring, W Wang, MB Major
|
| B.29 |
Developing a quantitative mass spectrometric-based assay to monitor global deubiquitinase activities in response to DUB inhibitor perturbation.
T Ma*, D Hewings, B Forrest, J Heideker, L Kategaya, A Fedorova, O Huang, J Lill, IE Wertz, K Yu
|
| B.30 |
Antibodies to biotin enable large-scale detection of biotinylation sites on proteins.
T Svinkina*, ND Udeshi, K Pedram, S Fereshetian, SA Myers, O Aygun, K Krug, K Clauser, D Ryan, T Ast, VK Mootha, AY Ting, SA Carr
|
| B.31 |
Direct in-gel profiling of protease specificity - DIPPS.
R Vidmar*, M Vizovisek, D Turk, B Turk, M Fonovic
|
| B.32 |
Identification of the Hedgehog Signalling Modulator Dynarrestin.
S Höing, T-Y Yeh, M Baumann, N Martinez, L Kremer, HCA Drexler*, P Kuchler, S Ziegler, P Reinhardt, P Habenberger, A Choidas, M Zischinsky, G Zischinsky, L Wagner, RM Abo-Rady, P Nussbaumer, B Klebl, T Schroer, HR Schöler, H Maldmann, JL Sterneckert
|
| B.33 |
Comprehensive proteome characterization and improved strategies for multi-PTM analysis.
J Oses-Prieto*, J Maynard, S Chand, AL Burlingame
|
| B.34 |
Library-Free DIA for PTM Identification and Quantification using PIQED: Application to Multiple Diet-Induced Acylation Changes in Mouse Liver Mitochondrial Proteins.
JG Meyer*, S Softic, N Basisty, G-X Wang, S Mukkamalla, H Steen, AI Nesvizhskii, E Verdin, BW Gibson, CB Newgard, CR Kahn, B Schilling
|
| B.35 |
Quantitative proteomic characterization of an isogenic model of the 22q11.2 syndrome deletion generated by CRISPR/Cas9 engineering.
Y-H Lin*, NP Paranjape, AP Wiita
|
| B.36 |
Coupling Semi-preparative SEC MS: Analysis of reduced and alkylated mAbs.
JH Robinson*, JO Hui, IDG Campuzano
|
