Program
This Symposium has Concluded
August: 16 | 17 | 18 | 19 | 20 | 21
Saturday, August 16
Symposium and Mini-Symposium Registration
Foyer, Monterey Room, Hotel Nikko, 222 Mason Street, San Francisco
| 3:00pm | Registration |
Sunday, August 17
Symposium and Mini-Symposium Registration
Nikko Ballroom Foyer
| 7:30am | Registration |
Mini-Symposium on Methods of Protein Quantitation and Dynamics
Nikko Ballroom
Chair: Daniel Liebler, Vanderbilt University School of Medicine, Nashville , TN, USA
| 8:30am | MS.1 | Improving the Robustness and Reproducibility of Mass Spectrometry Based Proteomics
Michael MacCoss, University of Washington, Seattle, WA, USA |
| 9:30 | MS.2 | SWATH-MS: Principles and Applications to Quantitative Biology
Ruedi Aebersold, ETH Zurich, Zurich, Switzerland |
| 10:10 | Coffee break | |
| 10:50 | MS.3 | Measuring cell signaling and pharmacodynamics using immuno-MRM
Jeffrey Whiteaker, Fred Hutchinson Cancer Research Center, Seattle, WA, USA |
| 11:30 | MS.4 | Improving multiplexing limits of parallel reaction monitoring (PRM) through longer one-dimensional chromatography and use of diverse retention time-normalized spectral libraries
Anatoly Urisman, University of California, San Francisco, California, USA |
| 12:10pm | Lunch | |
Chair: Steven A. Carr, The Broad Institute of MIT and Harvard Cambridge, MA, USA
| 1:40pm | MS.5 | Recent Advances in HRAM Quantification: Application to Clinical Assays
Bruno Domon, Centre de Recherche Public de la Santé (CRP-Santé), Strassen, Luxembourg |
| 2:20 | MS.6 | Expanding Roles of Targeted MS in Biology and Medicine
Hasmik Keshishian, The Broad Institute of MIT and Harvard, Cambridge, MA, USA |
| 3:00 | MS.7 | Emerging Approaches to Monitoring Chemotherapeutic Response
Arun Wiita, University of California, San Francisco, California, USA |
| 3:40 | MS.8 | Regulation of Protein Acylation by SIRT3 and SIRT5
Bradford Gibson, Buck Institute for Research on Aging, Novato, CA, USA |
Nikko Ballroom Vestibule
| 4:00pm | Symposium Registration | |
Monterey & Carmel Rooms
| 4:00pm | Symposium Poster Set-up | |
Golden Gate Room, 25th floor
| 6:00pm | Opening Reception | |
Monday, August 18
Nikko Ballroom Foyer
| 7:30am | Registration | |
Symposium: Emerging Challenges in Medicine and Biology
Nikko Ballroom
| 8:15am | Introduction
Ruedi Aebersold, A.L. Burlingame and Steven A. Carr |
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Chair: Arun Wiita, University of California, San Francisco, CA, USA
| 8:30am | 1.1 | Plenary Lecture Big Data and Human Disease: The New Era Michael Snyder, Stanford University, Stanford, California, USA |
Chair: Daniel Liebler, Vanderbilt University School of Medicine, Nashville , TN, USA
| 9:30am | 1.2 | Mass spectrometry based draft of the human proteome
Bernard Kuster, Technical University Munich, Freising, Germany |
| 10:10 | Coffee break | |
| 10:30 | 1.3 | Network Approaches to Aggregating Variants and Mutations.
Trey Ideker, University of California, San Diego, CA, USA |
| 11:10 | 1.4 | Single Cell Network Analysis in 3D
Bernd Bodenmiller, University of Zurich, Zurich, Switzerland |
| 11:50 | 1.5 | Spatially-resolved proteomic mapping of living cells (with a focus on mitochondria) using engineered peroxidase reporters
Alice Ting, Massachusetts Institute of Technology, Cambridge, MA, USA |
| 12:30pm | Lunch | |
Chair: Bradford Gibson, Buck Institute for Research on Aging, Novato, CA, USA
| 2:00pm | 2.1 | Use of Personalized Sequence Databases for Peptide MS/MS Spectrum Matching in the Proteogenomic Analysis of 105 TCGA Breast Tumors
Karl R. Clauser, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA |
| 2:40 | 2.2 | Proteogenomic analysis of human breast cancer connects genetic alterations to phosphorylation networks
Philipp Mertins, Broad Institute of MIT and Harvard, Cambridge, MA, USA |
| 3:20 | 2.3 | Proteogenomic Analysis of Human Colon and Rectal Cancer
Daniel Liebler, Vanderbilt University School of Medicine, Nashville , TN, USA |
Symposium Poster Session A
Monterey & Carmel Rooms
Co-Chairs: , University of California, San Francisco, California, USA
| 4:00pm | Poster Session A | |
Tuesday, August 19
Symposium: Methodologies Enabling New Insights into Biology I
Nikko Ballroom
Chair: Steven A. Carr, The Broad Institute of MIT and Harvard, Cambridge, MA, USA
| 8:30am | 3.1 | Plenary Lecture Systems analysis of mitochondrial pathogenesis. Vamsi Mootha, Harvard Medical School, Boston, MA, USA |
Chair: Anne-Claude Gingras, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ONT, Canada
| 9:30am | 3.2 | PTMomics - towards comprehensive quantitative analysis of multiple PTMs from biological material
Martin Larsen, University of Southern Denmark, Odense, Denmark |
| 10:10 | Coffee break | |
| 10:30 | 3.3 | Epigenetic and metabolic regulation by a family of new lysine acylation pathways
Yingming Zhao, University of Chicago, Chicago, IL, USA |
| 11:10 | 3.4 | Identification and characterization of caspase substrates that regulate axon degeneration in development and disease
Nicholas Hertz, Rockefeller University, New York, NY, USA |
| 11:50 | 3.5 | Proteomics and the functional organization of axons
Matthew Rasband, Baylor College of Medicine,Houston, TX, USA |
| 12:30pm | Lunch | |
Chair: Bernard Kuster, Technical University Munich, Freising, Germany
| 2:00pm | 4.1 | High resolution LC coupled with high resolution MS for in-depth proteomics
Yasushi Ishihama, Kyoto University, Kyoto, Japan |
| 2:40 | 4.2 | NeuCode Mouse and One Hour Proteomes
Joshua Coon, University of Wisconsin-Madison, Madison, WI, USA |
| 3:20 | 4.3 | How proteomics big data will transform mass spectrometry data analysis
Nuno Bandeira, University of California, San Diego, CA, USA |
Symposium Poster Session B
Monterey & Carmel Rooms
Co-Chairs: , University of California, San Francisco, California, USA
| 4:00pm | Poster Session B | |
Wednesday, August 20
Symposium: Methodologies Enabling New Insights into Biology II
Nikko Ballroom
Chair: Averil Ma, University of California, San Francisco, California, USA
| 8:30am | 5.1 | Resolving sites of protein palmitoylation using quantitative proteomics
Mark Collins, The University of Sheffield, England, UK |
| 9:10 | 5.2 | A novel comprehensive discovery approach for SUMO modified proteins.
Elizabeth Komives, University of California, San Diego, CA, USA |
| 9:50 | 5.3 | NeuCode Mass Spectrometry Unveils New Roles for Ubiquitin Machinery in Metabolic Homeostasis
Josh Baughman, Genentech, Inc., South San Francisco, CA, USA |
| 10:30 | Coffee break | |
Chair: Gerald Hart, Johns Hopkins University School of Medicine, Baltimore, MD, USA
| 10:50am | 5.4 | Plenary Lecture Functional Glycomics - Defining Glycan Recognition by Proteins Richard Cummings, Emory University, Atlanta, GA, USA |
| 11:50 | Lunch | |
Chair: Ruedi Aebersold, ETH Zurich, Zurich, Switzerland
| 1:20pm | 6.1 | Dynamic profiling of the protein life cycle reveals two distinct strategies for controlling differential expression of immune and housekeeping protein levels in response to pathogens
Marko Jovanovic, The Broad Institute of MIT and Harvard, Cambridge, MA, USA |
| 2:00 | 6.2 | High-Throughput Proteomic Mapping of Protein Interaction Networks: Toward a Global View of the Human Interactome
Edward L. Huttlin, Harvard Medical School, Boston, MA, USA |
Co-Chairs: , University of California, San Francisco, California, USA
| 2:40pm | Poster Session C | |
Conference Dinner
Nikko Ballroom
| 6:00pm | Conference Dinner Reception
Foyer, Nikko Ballroom? |
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| 7:00 | Conference Dinner
Nikko Ballroom |
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Thursday, August 21
Symposium: Methodologies Enabling New Insights into Biology III
Nikko Ballroom
Chair: Odile Burlet-Schiltz, Institute of Pharmacology and Structural Biology (IPBS), CNRS, Toulouse, France
| 8:30am | 7.1 | Proteomic Advances for Epigenetics Research
Ben Garcia, University of Pennsylvania Medical School, Philadelphia, PA, USA |
| 9:10 | 7.2 | Dissecting the role of the extracellular matrix in cancer progression: a proteomics-based approach
Alexandra Naba, Massachusetts Institute of Technology, Cambridge, MA, USA |
| 9:50 | 7.3 | Signaling interactome dynamics in health and disease
Anne-Claude Gingras, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ONT, Canada |
| 10:30 | Coffee break | |
| 11:00 | 7.4 | Structure of RNA polymerase II – Mediator holoenzyme investigated through an integrated mass spectrometry and electron microscopy approach.
Michael Trnka, University of California, San Francisco, CA, USA |
| 11:40 | Lunch | |
Chair: A.L. Burlingame, University of California, San Francisco, California, USA
| 1:40pm | 8.1 | Photo-cross-linking and high-resolution mass spectrometry for assignement of RNA-binding sites in RNA-binding proteins
Henning Urlaub, Max-Planck-Institute for Biophysical Chemistry, Goettingen, Germany |
| 2:20 | 8.2 | Cellular Immune Response versus Viral Immune Evasion: Lessons from Proteomics
Ileana Cristea, Princeton University, Princeton, NJ, USA |
| 3:00 | 8.3 | Genetic Variability and the Quantitative Proteome
Ruedi Aebersold, ETH Zurich, Zurich, Switzerland |
Chair: Ralph A. Bradshaw, University of California, San Francisco, California, USA
| 3:40pm | 8.4 | Plenary Lecture The interplay between protein phosphorylation and protein ubiquitylation in regulating the innate immune system Sir Philip Cohen, University of Dundee, Scotland, UK |
| 4:40pm | Closing remarks | |
| 5:00 | Adjourn | |
