Saida Patricia Salas-Castillo
Position
Specialist
Education
| M.Sc. | Biochemistry | 2007 | Universidad Nacional Autonoma de Mexico, Mexico |
| B.Sc. | Pharmaceutical Chemistry | 2004 | Benemérita Universidad Autónoma de Puebla, Mexico |
Work History
| 2007-Present: | Junior Specialist, Mass Spectrometry Facility, UCSF, San Francisco, CA. |
Research Interests
My interests are in the structural analysis of components present in scorpion venom, both to develop new improved de novo sequencing strategies using LC/MS, CID, and ECD and to decipher the amino acid sequence of the toxin components. As many bioactive components in venom target ion channels, this work should lead to the discovery of new biochemical tools for the analysis of ion channels in the nervous system.
Select Publications
Liao, M., Pabarcus, M.K., Wang, Y., Hefner, C., Maltby, D.A., Medzihradszky, K.F., Salas-Castillo, S.P., Yan, J., Maher, J.J., Correia, M.A., Impaired dexamethasone-mediated induction of tryptophan 2,3-dioxygenase in heme-deficient rat hepatocytes: translational control by a hepatic eIF2alpha kinase, the heme-regulated inhibitor, J Pharmacol Exp Ther. 323(3), 979-89 (2007). [Pubmed]
Batista, C.V., Román-González, S.A., Salas-Castillo, S.P., Zamudio, F.Z., Gómez-Lagunas, F., Possani, L.D., Proteomic analysis of the venom from the scorpion Tityus stigmurus: biochemical and physiological comparison with other Tityus species, Comp Biochem Physiol C Toxicol Pharmacol. 146(1-2), 147-57 (2007). [Pubmed]